Amazing Leftover Turkey Sandwich: 2 Ways

November 3, 2025
Written By Claire Sterling

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Ah, the day after Thanksgiving. The tryptophan has worn off, the dishes are piled high, but there’s one glorious thing left to look forward to: the ultimate leftover turkey sandwich. For me, it’s practically a holiday in its own right! Claire Sterling here, and just like my Grandma Sterling’s sunny kitchen in New England, the day after a big meal always felt special. While my corporate events career kept me busy, nothing beat the simple joy of a perfectly crafted sandwich made from the best bits of a feast. It’s not just about using up leftovers; it’s about recreating that incredible holiday magic, bite by savory, messy bite. This isn’t just a sandwich; it’s a whole Thanksgiving meal squished between two glorious slices of bread!

Why You’ll Love This Leftover Turkey Sandwich

Honestly, who doesn’t love a good leftover sandwich? This one practically makes itself!

  • Super Speedy: Ready in just minutes, perfect for when you’re feeling a little post-holiday lazy.
  • Packed with Flavor: It’s like Thanksgiving all over again, but in sandwich form. All those amazing tastes you just couldn’t get enough of!
  • Uses Up Those Delicious Leftovers: Makes the most of all that wonderful food you worked so hard to make (or have someone else make, no judgment here!).
  • Totally Customizable: You can throw in whatever other goodies you have lying around. Get creative!

Gather Your Leftover Turkey Sandwich Ingredients

Alright, let’s talk about what you’ll need to build this masterpiece. Think of it as picking out the best parts of the feast to build your dream sandwich. You don’t need a ton of fancy stuff, just the stars of the show, really!

Here’s what I usually grab:

  • Bread: 2 slices of sturdy bread are a must! I love sourdough or a good whole wheat because they hold up to all the goodness. Trust me, flimsy bread just won’t cut it here.
  • Turkey: About 1/2 cup of your best leftover roast turkey, sliced up nicely. Make sure it’s nice and tender!
  • Cranberry Sauce: 2 tablespoons of that sweet, tart cranberry sauce. It’s the perfect counterpoint to the savory turkey.
  • Stuffing: Roughly 1/4 cup of your leftover stuffing. This is a game-changer, adding that awesome texture and flavor. It’s optional, but oh-so-good!
  • Mayo: About a tablespoon of mayonnaise. It adds a little creaminess and helps everything stick together.
  • Butter: 1 teaspoon of butter, optional, but perfect if you’re toasting your bread for that extra crunch.
  • Lettuce: A few leaves of crisp lettuce, also optional, for a little freshness.
  • Gravy: A little bit of warm gravy if you’re going for the open-faced, extra-decadent version.

Crafting Your Ultimate Leftover Turkey Sandwich

Okay, so you’ve got your ingredients lined up, right? Now comes the truly fun part – building this edible masterpiece! This is where the magic happens, turning simple leftovers into something absolutely spectacular. It’s all about layering those flavors just right to get that perfect bite. I learned from my Grandma Sterling that even simple things deserve a little love and attention to make them extra special. So, let’s build the best leftover turkey sandwich you’ve ever had! It’s almost as satisfying as making the perfect grilled cheese sandwich.

Preparing the Bread for Your Leftover Turkey Sandwich

First things first, let’s tackle the bread. You want something that can hold up to all that delicious stuffing and turkey, so sturdy bread is key! I like to give mine a little toast. You can pop it in the toaster, or for extra amazing flavor, slather a little butter on the outside of each slice and grill them in a pan until golden brown and toasty. It makes all the difference, trust me!

Layering the Flavors for a Thanksgiving Leftover Sandwich

Now for the assembly line! Spread that creamy mayonnaise on one slice of your toasted bread. On the other slice, get a nice, even layer of your wonderful cranberry sauce. Then, pile on that tender, sliced turkey right on top of the mayo. If you’re feeling it, add a generous scoop of stuffing right over the turkey. It adds this amazing texture and deep flavor. You can totally add some crisp lettuce here too, if you like a little crunch.

Creating the Open-Faced Turkey Sandwich with Gravy

For those who want something a little more… well, *decadent*, let’s talk about the open-faced version! Take one slice of your prepared bread, pile high with that beautiful turkey and stuffing. If you have some cheese handy, lay a slice on top. Pop it under the broiler for just a minute or two until that cheese is melty and gorgeous. Then, the grand finale: pour that warm, savory gravy right over everything. It’s like a mini Thanksgiving dinner on a plate!

Tips for the Perfect Leftover Turkey Sandwich

Alright, let’s talk about making your leftover turkey sandwich absolutely sing! It’s not just about throwing stuff between bread; a little bit of know-how goes a long way. First off, the dreaded sogginess – nobody wants a floppy sandwich that falls apart! My best advice? Use hearty bread, like the sourdough or whole wheat I mentioned. And if you’re not eating it right away, keep the wet stuff, like cranberry sauce and gravy, separate until you’re ready to dive in. A quick toast of the bread really helps create a little barrier too. And don’t be afraid to experiment – my Grandma Sterling always said that a dash of something unexpected, like a little pickle relish or a smear of mustard, can make a classic even better!

Variations on Your Thanksgiving Leftover Sandwich

Okay, so we’ve covered the classics, but the fun doesn’t stop there! This Thanksgiving leftover sandwich is just begging for your personal touch. Don’t be shy! Feeling adventurous? Try a smear of Dijon mustard for a little tang, or maybe some leftover mashed potatoes if you’re feeling *really* wild! A different cheese, like sharp cheddar, melted on top of the hot turkey can be divine. Honestly, whatever delicious bits you have left from the feast can find a happy home in this glorious sandwich!

Frequently Asked Questions about Leftover Turkey Sandwiches

Got questions? I’ve got answers! Making the perfect post-holiday sandwich is my jam, so let’s make sure yours is spectacular too!

What’s the best bread for a leftover turkey sandwich?

For the ultimate bite, you really want a bread that can stand up to all those yummy fillings. Think hearty sourdough, a good whole wheat, or even a sturdy ciabatta roll. They won’t get soggy as easily!

Can I make a turkey cranberry stuffing sandwich ahead of time?

You can definitely assemble it ahead, but for the freshest taste, I’d keep the wet stuff like gravy or extra cranberry sauce separate until you’re ready to eat. Toasted bread helps too!

What other Thanksgiving leftovers work well in a sandwich?

Oh, the possibilities! Mashed potatoes, a little bit of stuffing (of course!), roasted veggies, or even a dollop of green bean casserole can be amazing additions. Get creative!

Nutritional Information for Your Leftover Turkey Sandwich

Now, I’m no nutritionist, but I can give you a ballpark of what you’re packing into this delicious creation. Remember, these numbers are just estimates and can totally change depending on exactly how much turkey you pile on, what kind of bread you use, and if you go extra heavy on the mayo (no judgment!).

Estimated per sandwich:

  • Calories: Around 450
  • Total Fat: About 20g (with 5g saturated)
  • Protein: Roughly 30g
  • Carbohydrates: Around 40g

This counts as one glorious sandwich, so enjoy every bite knowing you’re having a mini Thanksgiving feast!

Share Your Ultimate Gobbler Sub Creation!

Alright, you’ve built your masterpiece! Now tell me all about it! Did you go classic, or did you invent something totally new? Drop a comment below to share your favorite way to make the ultimate gobbler sub, or rate this recipe and let me know how it turned out. And hey, if you share a pic on social media, be sure to tag us – I’d love to see your delicious creations!

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The Ultimate Leftover Turkey Sandwich

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Transform your Thanksgiving leftovers into the best sandwich of the year. This recipe guides you through creating a delicious and satisfying turkey sandwich, perfect for enjoying the holiday flavors again.

  • Author: Claire
  • Prep Time: 5 min
  • Cook Time: 5 min
  • Total Time: 10 min
  • Yield: 1 sandwich 1x
  • Category: Sandwich
  • Method: Assembly
  • Cuisine: American
  • Diet: Vegetarian

Ingredients

Scale
  • 2 slices sturdy bread (sourdough or whole wheat recommended)
  • 1/2 cup leftover roast turkey, sliced
  • 2 tablespoons cranberry sauce
  • 1/4 cup leftover stuffing (optional)
  • 1 tablespoon mayonnaise
  • 1 teaspoon butter (optional, for toasting)
  • Lettuce leaves (optional)
  • Gravy (optional, for open-faced version)
  • Cheese (optional, for open-faced version)

Instructions

  1. If desired, lightly toast your bread slices. You can also spread a thin layer of butter on the outside of each slice and toast them in a pan for extra flavor and crispness.
  2. Spread mayonnaise on one slice of bread.
  3. On the other slice, spread the cranberry sauce.
  4. Layer the sliced turkey over the mayonnaise.
  5. If using, add a layer of stuffing on top of the turkey.
  6. Add lettuce leaves if desired.
  7. Close the sandwich with the cranberry-sauce-covered bread slice.
  8. For an open-faced version, place the turkey and stuffing on one slice of toasted bread, top with cheese if using, and warm under a broiler or in a toaster oven until cheese is melted. Pour warm gravy over the top.

Notes

  • For a hot sandwich, consider adding a slice of cheese and warming the sandwich in a pan or panini press.
  • Don’t be afraid to experiment with other Thanksgiving leftovers like mashed potatoes or green bean casserole.
  • Using sturdy bread or rolls will help prevent the sandwich from becoming soggy.

Nutrition

  • Serving Size: 1 sandwich
  • Calories: 450
  • Sugar: 15g
  • Sodium: 800mg
  • Fat: 20g
  • Saturated Fat: 5g
  • Unsaturated Fat: 15g
  • Trans Fat: 0g
  • Carbohydrates: 40g
  • Fiber: 3g
  • Protein: 30g
  • Cholesterol: 80mg

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